Identification of predictive biomarkers for COVID-19 severity: By employing an integrative multi-omics approach, a team of scientists at IOB and Pandey lab have identified a set of biomarkers which can be exploited to predict a more severe course in clinical COVID-19 outcomes. The findings are published in The Lancet Digital Health.

Interactome of SARS-CoV-2 proteins and human ion channels: Using machine learning based approaches protein-protein interactions between human ion-channels and SARS-CoV-2 proteins were predicted and the host pathways involving these interactions were studied by a team of scientists at IOB. The findings of the study are published in the journal Pathogens.

Profiling of glycopeptides of chondroitin sulfate proteoglycans: Scientists from IOB have developed a method to characterize chondroitin sulfate proteoglycan (CSPG) using mass spectrometry. The study carried out is published in the journal Journal of Proteins and Proteomics.

Pan-cancer quantitation of epithelial-mesenchymal transition dynamics using targeted proteomics approach for advancing novel therapeutics: Scientists from IOB have developed a parallel reaction monitoring-based targeted proteomics method for quantifying abundances of EMT-associated proteins across cancer cell lines. The results from the above study were published in Journal of Translational Medicine.

Identification of Proteomic Signatures in Diffuse and Intestinal Subtypes of Gastric Cancer: IOB scientists designed a study to identify the differences between diffuse and intestinal subtypes of gastric cancer at the protein level using high-resolution mass spectrometry. The findings of the study was published in Cancers..

Alterations in Ion Channels and Their Correlation with Epithelial to Mesenchymal Transition in Breast Cancer: A systems biology based approach was employed by a team of scientists at IOB to identify the altered ion channels co-expressed with epithelial to mesenchymal transition related genes in breast cancer patients and their further repercussions were discussed. The findings are published in Cancers..