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  Department of Biotechnology, Government of India provided a grant support to Institute of Bioinformatics and NIMHANS to carry out proteomic investigation to analyze neurological diseases.
     
  IOB is recognized as a research center for award of Ph.D. degrees with Manipal University.
     
  IOB is recognized as a research center for award of Ph.D. degrees with Kuvempu University.
  IOB is recognized as a research center for award of Ph.D. degrees with Amrita University.
     
  IOB is recognized as a research center for award of Ph.D. degrees with Pondicherry University.
 
 

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The Team

Research Lab

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TSQ Quantam Ultra Mass Spectrometer

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LTQ Orbitrap Velos Mass Spectrometer

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Research
 
Resource of Asian Primary Immunodeficiency Disease (RAPID): IOB Scientists have developed database of Primary Immunodeficiency Disease genes known as 'Resource of Asian Primary Immunodeficiency Disease (RAPID)' in collabration with RIKEN, Japan. We have also developed algorithm for the prediction of candidate primary Immunodeficiency disease genes using support vector machine learning approach Results of these studies have been published in 'Nucleic Acids Research' and 'DNA Research' respectively.

Molecular profiling of Embryonic Stem Cells and Embryonic Carcinoma Cells: Scientists from IOB and Pandey lab have identified key molecules that differentiate embryonic stem cells from embryonic carcinoma cells by quantitative proteomics. The findings from the above study was published in the journal Proteomics.

Investigation of Molecular Markers of Neuronal Differentiation: Using advanced labeling technology, molecular markers of differentiation of motor neurons and astrocytes from embryonic stem cells were identified in a collaborative study between IOB, Pandey lab and Institute of Cell Engineering, Johns Hopkins University Findings from this study are published in Journal of Proteome Research.
Quantitative Proteomic Investigation of Hepatocellular Carcinoma: IOB scientists unveil the first large scale quantitative proteomic profiling of hepatocellular carcinoma using robust discovery platforms such as iTRAQ labeling and high resolution mass spectrometry. The study revealed several novel and known upregulated proteins as potential biomarkers in hepatocellular carcinoma and results are published Journal of Proteome Research.
  Research
 

IOB mapped the human proteome for the first time:
Researchers from the Institute of Bioinformatics, Bangalore, as part of a 72-member team, have for the first time deciphered a near complete protein map of human beings. Results from this landmark study is featured on the cover of the prestigious journal Nature  
 
NDTV coverage on the Human Proteome Map


Click here to view more news articles on Human Proteome Map

 
 
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