Proteinpedia: IOB scientists
create the largest community resource of experimental data in human proteins.
It is a portal for sharing and integration of human protein data. The international
collaborative work is published in February issue of Nature
Molecular profiling of Embryonic Stem Cells and Embryonic
Carcinoma Cells: Scientists from IOB and
Pandey lab have identified key molecules that differentiate embryonic
stem cells from embryonic carcinoma cells by quantitative proteomics.
The findings from the above study was published in the journal Proteomics.
Investigation of Molecular
Markers of Neuronal Differentiation: Using advanced labeling
technology, molecular markers of differentiation of motor neurons and
astrocytes from embryonic stem cells were identified in a collaborative
study between IOB, Pandey lab and Institute of Cell Engineering, Johns
Hopkins University Findings from this study are published in Journal
of Proteome Research.
Quantitative Proteomic Investigation
of Hepatocellular Carcinoma: IOB scientists unveil the first
large scale quantitative proteomic profiling of hepatocellular carcinoma
using robust discovery platforms such as iTRAQ labeling and high resolution
mass spectrometry. The study revealed several novel and known upregulated
proteins as potential biomarkers in hepatocellular carcinoma and results
are published Journal of Proteome Research.
expression studies in Esophageal Squamous Cell Carcinoma: Scientists
at IOB used a combination of DNA microarrays and immunohistochemical
labeling of tissue microarrays to delineate gene expression
patterns in cancer of esophagus and subsequently to validate
molecular signatures specific to this cancer. Results of this
investigation are published in Cancer
Biology and Therapy.
IOB scientists assemble and analyze the largest interactome in humans:
The 'circuitry' in human cells was
analyzed by IOB scientists and published in Nature
IOB mapped the human proteome for the first time: Researchers from the Institute of Bioinformatics, Bangalore, as part of a 72-member team, have for the first time deciphered a near complete protein map of human beings. Results from this landmark study is featured on the cover of the prestigious journal
NDTV coverage on the Human Proteome Map
Click here to view more news articles on Human Proteome Map
IOB's contribution to the India's Research Landscape: The
Department of Science and Technology (DST), Government of
India published "India's Research Landscape: Output, Collaboration and Comparative Performance - Bibliometric Studies" on February 17, 2016, which consisted of two reports.
First report compiled by Thomson Reuters and entitled "India's Research Output and Collaboration (2005-14): A Bibliometric Study" while the other report was independently compiled by
Elsevier and entitled "International Comparative Performance of India's Research Base (2009-14)."
In Thomson Reuters report "Human Protein Reference Database" paper published in the year 2009 is ranked second among the Top 10 Publications with Indian Affiliation in the area of Biology and Biochemistry and "A draft map of human proteome" featured
on the cover of Nature in 2014, was found to be cited more than 400 times
within a short span and is ranked sixth.
In Elsevier report Human Protein Reference Database" is ranked second
in the area of Biochemistry, Genetics and Molecular Biology with 1,029