Molecular Biology Lab
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  Department of Biotechnology, Government of India provided a grant support to Institute of Bioinformatics and NIMHANS to carry out proteomic investigation to analyze neurological diseases.
  IOB is recognized as a research center for award of Ph.D. degrees with Manipal University.
  IOB is recognized as a research center for award of Ph.D. degrees with Kuvempu University.
  IOB is recognized as a research center for award of Ph.D. degrees with Amrita University.
  IOB is recognized as a research center for award of Ph.D. degrees with Pondicherry University.


The Team

Research Lab


TSQ Quantam Ultra Mass Spectrometer


LTQ Orbitrap Velos Mass Spectrometer

Resource of Asian Primary Immunodeficiency Disease (RAPID): IOB Scientists have developed database of Primary Immunodeficiency Disease genes known as 'Resource of Asian Primary Immunodeficiency Disease (RAPID)' in collabration with RIKEN, Japan. We have also developed algorithm for the prediction of candidate primary Immunodeficiency disease genes using support vector machine learning approach Results of these studies have been published in 'Nucleic Acids Research' and 'DNA Research' respectively.

Molecular profiling of Embryonic Stem Cells and Embryonic Carcinoma Cells: Scientists from IOB and Pandey lab have identified key molecules that differentiate embryonic stem cells from embryonic carcinoma cells by quantitative proteomics. The findings from the above study was published in the journal Proteomics.

Investigation of Molecular Markers of Neuronal Differentiation: Using advanced labeling technology, molecular markers of differentiation of motor neurons and astrocytes from embryonic stem cells were identified in a collaborative study between IOB, Pandey lab and Institute of Cell Engineering, Johns Hopkins University Findings from this study are published in Journal of Proteome Research.
Quantitative Proteomic Investigation of Hepatocellular Carcinoma: IOB scientists unveil the first large scale quantitative proteomic profiling of hepatocellular carcinoma using robust discovery platforms such as iTRAQ labeling and high resolution mass spectrometry. The study revealed several novel and known upregulated proteins as potential biomarkers in hepatocellular carcinoma and results are published Journal of Proteome Research.

Two Ph.D. students from IOB have received awards for their presentation at Amrita BioQuest International Conference on Biotechnology for innovative applications held in Amrita University, Kerala, India.

Tejaswini Subbannayya was awarded first prize in Delegate Talks under the Bioanalytical Techniques category on "Proteomic profiling of gallbladder cancer secretome – a source for circulatory biomarker discovery".

Dr. Krishna R. Murthy's talk on "Proteomic analysis of human vitreous humor" was awarded second prize in Ten Talks category.


Institute of Bioinformatics was actively involved in organizing and participating in the second Elsevier's 'CodeForScience' (CSF) event that was successfully concluded on July 29th, 2012 by an Awards ceremony held at the Indian Institute of Science, Bangalore. BabyLakshmi Muthusamy, Harsha Gowda and Joji Kurian Thomas won second prize in the concept formulation and development rounds at the event. This was featured in an article in Times of India.


An article that appeared in The Hindu covered a new collaboration planned between Madurai Kamaraj University and the Institute of Bioinformatics. MKU is going to sign an MoU with IOB for exploring training and research collaboration in the field of bioinformatics, genomics, transcriptomics and proteomics between the two leading institutions.


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